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Nakon ponavljane primene leka tokom nekoliko nedelja može doći do određenog gubitka hipnotičkih efekata.

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Hronična upotreba (čak i terapijskih doza) može dovesti do razvoja fizičke i psihičke zavisnosti: prekid terapije može dovesti do pojave rebound fenomena ili fenomena obustave (videti odeljak four.4). Prijavljena je i zloupotreba benzodiazepina.

Antivirusni lekovi inhibiraju CYP3A4 metabolički place diazepama. Povećan je rizik od sedacije i respiratorne depresije. Zbog toga treba izbegavati istovremenu upotrebu.

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Research in Women of all ages breastfeeding have demonstrated damaging toddler results. A substitute for this medication should be prescribed or you need to end breastfeeding when applying this drugs.

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Ukoliko je lekar propisao uzimanje leka Bensedin pre hirurške intervencije, uobičajena doza je 2 mg